Re: Myocardial infarction and ventricular rupture.

Ventricular septal rupture after acute myocardial infarction.

Ventricular septal rupture is a rare complication of acute myocardial infarction with important hemodynamic consequences. Spontaneous closure is extremely rare. Without a rapid diagnosis and correction by surgical intervention, the short-term mortality of these patients is higher than 90%. We report the case of a patient with acute myocardial infarction and a ventricular septal rupture that was...

Ventricular free wall rupture after myocardial infarction

Patients with their first myocardial infarction (MI), who present to the emergency department many hours after the onset of chest pain, who appear to be improving but suddenly develop new chest pain and unexpected hypotension (with or without signs of cardiac tamponade), should be suspected of having ventricular free wall rupture (VFWR). The mainstay of treatment is surgery. These patients may ...

Myocardial infarction with ventricular septal rupture and cardiogenic shock.

A 72-year-old woman with a history of systemic arterial hypertension presented to the emergency department with chest pain, and an electrocardiogram showed acute anterior myocardial infarction with striking ST-segment elevation, upright T waves, and large Q waves in leads V1 to V4 (Figure). Furthermore, the ST-segment elevation > 0.25 mV in lead V1, the ST depression ≥ 0.1 mV in lead III, and t...

Posttraumatic left ventricular myocardial infarction and rupture in infancy.

MicroRNAs, Innate Immunity and Ventricular Rupture in Human Myocardial Infarction

MicroRNAs are non-coding RNAs, functionioning as post-transcriptional regulators of gene expression. Some microRNAs have been demonstrated to play a role in regulation of innate immunity. After myocardial infarction (MI), innate immunity is activated leading to an acute inflammatory reaction. There is evidence that an intense inflammatory reaction might contribute to the development of ventricu...